Diabetes Mellitus

Diabetes Mellitus is a chronic metabolic disorder characterized by elevated levels of glucose (sugar) in the blood, resulting from defects in insulin production, insulin action, or both. It is classified primarily into two types: Type 1 diabetes, where the body fails to produce sufficient insulin, and Type 2 diabetes, which is characterized by the body's ineffective use of insulin. A third category, gestational diabetes, occurs during pregnancy and typically resolves after childbirth, though it increases the risk of developing Type 2 diabetes later in life. Testosterone plays a role in glucose metabolism and insulin sensitivity, and low testosterone levels have been linked to an increased risk of developing Type 2 diabetes in men. This association is thought to be related to the role of testosterone in maintaining muscle mass (which impacts glucose utilization) and fat distribution, factors that influence insulin resistance. Treatment of diabetes involves managing blood sugar levels through diet, exercise, medication, and monitoring. In men with low testosterone levels and diabetes, testosterone replacement therapy (TRT) has been shown to improve insulin sensitivity and glycemic control, highlighting the interconnectedness of hormonal health and metabolic diseases. However, TRT should be approached with caution and under medical supervision, especially in patients with complex health conditions like diabetes.