Androgenetic Alopecia

Androgenetic alopecia, widely recognized as male-pattern baldness in men and female-pattern hair loss in women, is the most common type of hair thinning and loss that affects both sexes. This condition is primarily driven by a combination of genetics and the action of androgens, particularly dihydrotestosterone (DHT), a more potent derivative of testosterone. In susceptible individuals, hair follicles shrink over time under the influence of DHT, leading to shorter and finer hair until, eventually, hair growth stops altogether. The pattern of hair loss typically follows a characteristic path, with men experiencing receding hairlines and bald spots on the crown, while women tend to experience thinning hair across the top of the scalp while maintaining the hairline. The severity and progression of androgenetic alopecia vary widely and are influenced by genetic predisposition, hormonal levels, and age. While there is no cure for androgenetic alopecia, treatment options are available that can slow hair loss, stimulate hair growth, or improve hair appearance. These treatments include topical applications such as minoxidil, oral medications like finasteride for men, and, in some cases, hair transplant surgery. Understanding the role of androgens in this condition is crucial for effective management and therapy selection.